AHK-Cu

Description

AHK-Cu (50mg/100mg) (Alanyl-L-histidyl-L-lysine Copper(II) Complex) is a high-purity, research-grade synthetic copper-tripeptide chelate specifically engineered for dermatological and follicular biology investigations. Structurally distinct from its GHK analogue by an N-terminal alanine substitution, AHK-Cu is commonly examined in preclinical and in vitro investigations focused on hair follicle morphogenesis, microvascular perfusion, and cellular apoptosis regulation.

In laboratory cell-culture and tissue explant models, AHK-Cu is widely studied for its ability to stimulate the proliferation of human dermal papilla cells (hDPCs) and modulate key molecular markers of the follicular growth (anagen) phase. Research indicates that the complex upregulates the expression of vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF-7/bFGF), while downregulating transforming growth factor-beta 1 (TGF-β1)—a key mediator of apoptotic follicle regression. Additionally, through its role as a bio-carrier for ionic copper (Cu2+), AHK-Cu supports copper-dependent enzymatic processes, including lysyl oxidase activity and superoxide dismutase (SOD) antioxidant defense, facilitating extracellular matrix cross-linking and fibroblast survival. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 50mg or 100mg per vial (as specified)
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide complex
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving copper-peptide delivery kinetics, dermal papilla signaling pathways, angiogenic growth factor regulation, and extracellular matrix synthesis investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing AHK-Cu (50mg/100mg) from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.