PT-141-10mg

Description

PT-141 10mg (also known as Bremelanotide / Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH) is a high-purity, research-grade synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH). Derived as a central-acting metabolite of Melanotan II via C-terminal deamidation to a free carboxylic acid, it is commonly examined in preclinical and in vitro investigations focused on melanocortinergic neurocircuitry, central autonomic regulation, and behavioral neuroendocrinology.

Unlike vascular-targeted compounds, PT-141 operates centrally within the central nervous system (CNS). It displays potent agonist activity across melanocortin receptor subtypes, primarily targeting the melanocortin 3 receptor (MC3R) and melanocortin 4 receptor (MC4R) concentrated in the medial preoptic area (mPOA), paraventricular nucleus (PVN), and hypothalamus. Researchers utilize this compound to analyze the downstream stimulation of dopamine, oxytocin, and norepinephrine release, mapping the neurochemical modulation of autonomic and motivational responses without inducing direct peripheral vasodilation. Additionally, its selective activity allows laboratory exploration of central appetite networks, neuroprotection models, and blood pressure regulation cascades. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 10mg per vial
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving central melanocortin receptor (MC3R/MC4R) kinetics, hypothalamic neuroendocrine signaling, and behavioral pathway investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing PT-141 10mg from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.