Semax

Description

Semax (5mg/10mg) is a high-purity, research-grade synthetic heptapeptide with the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). Structurally engineered as an analogue of the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10) stabilized with a C-terminal Pro-Gly-Pro tripeptide sequence, Semax exhibits extended biological half-life and enzymatic stability while lacking systemic hormonal or steroidogenic activity. It is commonly examined in preclinical and in vitro investigations focused on neurobiology, synaptic plasticity, and cerebral ischemia models.

In laboratory environments, Semax is widely used to study the rapid transcriptional upregulation and sustained expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and their corresponding receptor tyrosine kinases (TrkB and TrkA) within hippocampal and cortical structures. Additionally, researchers evaluate its modulation of central monoaminergic turnover (dopamine and serotonin systems), its influence on microvascular endothelial gene expression, and its anti-inflammatory properties through the downregulation of pro-inflammatory cytokines and mitigation of oxidative neurotoxicity. Consequently, it serves as a primary experimental tool for analyzing cognitive consolidation mechanisms, neurovascular repair kinetics, and neurodegenerative stress-adaptation pathways. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 5mg or 10mg per vial (as specified)
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving neurotrophin (BDNF/NGF) signaling kinetics, central neurovascular dynamics, and neuroprotective pathway investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing Semax (5mg/10mg) from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.