MOTS-c

Description

MOTS-c (10mg/20mg/40mg) (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a high-purity, research-grade synthetic 16-amino acid mitochondrial-derived peptide (Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg). It is commonly examined in preclinical and in vitro investigations focused on cellular energetic signaling, metabolic adaptation, and mitochondrial-nuclear retrograde communication. It is widely used in laboratory environments to study the biochemical regulation of the AMP-activated protein kinase (AMPK) pathway and the suppression of the folate-methionine cycle.

Its well-characterised ability to translocate to the nucleus in response to metabolic stress allows researchers to investigate peptide-mediated transcriptional regulation of adaptive stress-response genes, glucose utilization kinetics, and fatty acid oxidation dynamics. Through these mechanisms, MOTS-c promotes cellular insulin sensitivity, stimulates GLUT4 transporter translocation independently of insulin signaling, and enhances skeletal muscle metabolic capacity. This makes it an essential tool for evaluating metabolic flexibility, insulin resistance models, cellular senescence mitigation, and biogerontology pathways. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 10mg, 20mg, or 40mg per vial (as specified)
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving mitochondrial-derived peptide signaling kinetics, AMPK pathway activation, and cellular metabolic homeostasis investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing MOTS-c (10mg/20mg/40mg) from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.