Description
Melanotan II (MT-2 Acetate) 10mg (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) is a high-purity, research-grade synthetic cyclic heptapeptide analogue of endogenous alpha-melanocyte-stimulating hormone (α-MSH), presented in its stable acetate salt form. It is commonly examined in preclinical and in vitro investigations focused on melanocortin receptor subtype signaling, melanogenesis activation, and central autonomic regulation. It is widely used in laboratory environments to study the non-selective agonism of melanocortin receptors, displaying high affinity for MC1R, MC3R, MC4R, and MC5R subtypes.
Through its binding to the MC1 receptor on cutaneous melanocytes, MT-2 is utilized to investigate the intracellular activation of adenylate cyclase, cyclic AMP (cAMP) upregulation, and the downstream transcription of tyrosinase—the rate-limiting enzyme in eumelanin synthesis. Concurrently, its interaction with central MC3 and MC4 receptors located in the hypothalamus allows researchers to evaluate central neuroendocrine cascades, appetite regulation kinetics, lipid metabolism, and autonomic nervous system responses. This versatile pharmacology makes it a key tool for analyzing photoprotective cellular mechanisms, neurocircuitry modulation, and metabolic homeostasis research. This compound is supplied in a lyophilised form suitable for controlled research applications.
Product Specifications:
- Quantity: 10mg per vial
- Purity: Research-grade, verified via laboratory testing
- Form: Lyophilised peptide (acetate salt)
- Storage: Store in a cool, dry environment away from direct light
Intended Use:
This product is intended exclusively for laboratory, academic, and controlled research purposes involving melanocortin receptor (MC1R-MC5R) signaling kinetics, melanogenesis pathways, and central neuroendocrine metabolic investigations.
Disclaimer:
All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.
Terms of Sale:
By purchasing Melanotan II (MT-2 Acetate) 10mg from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.


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