Kisspeptin-10mg

Description

Kisspeptin 10mg (also commonly investigated as Kisspeptin-10 / metastin fragment) is a high-purity, research-grade synthetic peptide analogue corresponding to the biologically active C-terminal decapeptide sequence derived from the KISS1 gene product. It is commonly examined in preclinical and in vitro investigations focused on the hypothalamic-pituitary-gonadal (HPG) axis, reproductive endocrinology, and tumor metastasis suppression kinetics. It is widely used in laboratory environments to study the high-affinity binding and activation of the G-protein-coupled receptor GPR54 (KISS1R).

Upon binding to KISS1R located on hypothalamic gonadotropin-releasing hormone (GnRH) neurons, Kisspeptin activates the Gαq/11-phospholipase C (PLC)-inositol triphosphate (IP3)/diacylglycerol (DAG) signaling pathway, driving intracellular calcium mobilization and stimulating the pulsatile release of endogenous GnRH. This cascade subsequently modulates the downstream secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary gland. Additionally, researchers evaluate its role as a metastasis suppressor (metastin) by studying its ability to attenuate cellular migration, matrix metalloproteinase expression, and invasive phenotype signaling in malignant cell lines. Consequently, Kisspeptin serves as an essential tool for evaluating neuroendocrine pulse generation, pubertal signaling cascades, and reproductive axis feedback regulation. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 10mg per vial
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving GPR54/KISS1R receptor kinetics, hypothalamic GnRH pulsatile regulation, and neuroendocrine reproductive signaling pathway investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing Kisspeptin 10mg from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.