NAD+

Description

NAD+ (500mg/1000mg) (Nicotinamide Adenine Dinucleotide, oxidized form) is a high-purity, research-grade essential pyridine dinucleotide coenzyme present in all living cells. It is commonly examined in preclinical and in vitro investigations focused on mitochondrial energy transduction, cellular longevity cascades, and epigenetic enzyme regulation. In laboratory environments, it is widely utilized to study electron transfer kinetics within the mitochondrial respiratory chain (interconverting between NAD+ and NADH) to support adenosine triphosphate (ATP) production via oxidative phosphorylation and glycolysis.

Beyond its role as an enzymatic cofactor, NAD+ functions as an indispensable rate-limiting cosubstrate for critical regulatory enzymes, including NAD+-dependent deacetylases (Sirtuins, SIRT1–SIRT7), poly(ADP-ribose) polymerases (PARPs involved in genomic DNA damage response), and cyclic ADP-ribose synthases (such as CD38 and CD157). Researchers analyze the depletion and replenishment kinetics of the intracellular NAD+ pool to explore mitochondrial biogenesis, oxidative stress resistance, chromatin remodeling, and metabolic resilience. This makes it a foundational tool for evaluating metabolic decline models, neuroprotective mechanisms, biogerontological signaling, and cellular homeostasis research. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 500mg or 1000mg per vial (as specified)
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised dinucleotide coenzyme (oxidized form)
• Storage: Store in a cool, dry environment away from direct light (recommended -20°C for long-term storage)

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving cellular redox kinetics, sirtuin signaling pathways, mitochondrial bioenergetics, and DNA repair mechanism investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing NAD+ (500mg/1000mg) from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.