Tesamorelin-10mg

Description

Tesamorelin 10mg (trans-3-hexenoyl-hGRF 1-44 NH2) is a high-purity, research-grade synthetic 44-amino acid peptide analogue of endogenous human growth hormone-releasing factor (hGRF), modified via the addition of a trans-3-hexenoyl moiety at its N-terminus. This structural modification confers enhanced metabolic stability and resistance to enzymatic cleavage by dipeptidyl peptidase-4 (DPP-4) compared to native GHRH. It is commonly examined in preclinical and in vitro investigations focused on anterior pituitary receptor kinetics, somatotroph signaling cascades, and visceral adipose tissue metabolism.

Its primary mechanism involves high-affinity binding to pituitary GHRH receptors, activating the adenylate cyclase-cAMP signaling pathway to stimulate the synthesis and pulsatile, physiologic secretion of endogenous growth hormone (GH). In laboratory models, researchers evaluate its downstream effects on hepatic insulin-like growth factor 1 (IGF-1) gene expression, visceral lipid mobilization, beta-oxidation upregulation, and hepatic steatosis reduction pathways without disrupting basal glycemic homeostasis. Consequently, Tesamorelin serves as a specialized tool for analyzing selective lipolytic signaling, body composition remodeling mechanics, and somatotropic neuroendocrine feedback loops. This compound is supplied in a lyophilised form suitable for controlled research applications.

Product Specifications:

• Quantity: 10mg per vial
• Purity: Research-grade, verified via laboratory testing
• Form: Lyophilised peptide
• Storage: Store in a cool, dry environment away from direct light

Intended Use:

This product is intended exclusively for laboratory, academic, and controlled research purposes involving GHRH receptor binding kinetics, pulsatile somatotropic signaling, and visceral adipocyte lipolytic pathway investigations.

Disclaimer:

All information provided is for scientific, educational, and reference purposes only. This product has not been evaluated or approved by any regulatory authority. It is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for human or animal consumption. The purchaser assumes full responsibility for proper handling, storage, and lawful use in a research setting.

Terms of Sale:

By purchasing Tesamorelin 10mg from TRUEBASE PEPTIDES, you confirm that you are a qualified professional, researcher, or institution with the expertise required to safely handle and study research compounds. TRUEBASE PEPTIDES shall not be held liable for misuse, improper handling, or any consequences arising from unauthorised application of this compound.